a change in bowel habits prompts a 53-year-old woman to see her physician. on physical examination there are no lesions noted on digital rectal examination, but her stool is positive for occult blood. a colonoscopy is performed and reveals a 6 cm friable mass inthe cecum. a biopsy of this mass is performed and microscopic examination shows a moderately differentiated adenocarcinoma. after resection of the tumor, the oncologist begins treatment with 5-fluorouracil (5-fu) combined with other chemotherapeutic agents. 5-fu not only kills tumor cells but also rapidly growing cells of the immune system and intestine. what is the mechanism by which 5-fu selectively kills fast growing cells? group of answer choices binds tightly to thymidylate synthase inhibiting the synthesis of thymidine binds tightly to rna polymerase ii shutting down transcription of mrna binds tightly to dna polymerase shutting down replication intercalates between the two strands of dna preventing replication binds tightly to rna polymerase i shutting down synthesis of rrna

Answers

Answer 1

RAS change in the cancerous cells. RAS mutations are frequently seen in human carcinomas and play a role in oncogenesis. Multiple mutations are typically present, and there might be many different kinds of mutations.

Chemotherapy is required for adenocarcinoma?

Unfortunately, chemotherapy is not frequently used as the primary treatment for small intestinal adenocarcinoma because it isn't really particularly susceptible to it. But in other circumstances, it might be appropriate: if the cancer has migrated (metastasized) to different body regions.

What's the best method of adenocarcinoma treatment?

Surgery: Surgery is frequently performed as the initial form of adenocarcinoma treatment to remove the malignant glandular tissue as well as some surrounding tissue. To reduce healing, minimally invasive surgical techniques may be performed.

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Related Questions

We often see soccer players suffering from muscle crime during the game. As a science student how would you explain this process to your friends

Answers

Answer: The a

Explanation:

ssdjfv

What are some examples of global factors (e.g., technology, economics, ecology, climate, society) that couldhave facilitated the spread of Zika?

Answers

Some examples of global factors that could have facilitated the spread of Zika virus include climate change, increased international travel, urbanization, and globalization.

Climate change may have contributed to the spread of Zika by creating more suitable environments for the mosquito vector, Aedes aegypti, which thrives in warmer and more humid conditions.

Increased international travel and trade have facilitated the rapid spread of the virus from one region to another.

Urbanization and population growth have created more densely populated areas, providing more opportunities for mosquitoes to breed and spread the virus.

Globalization has also increased the demand for goods and services, resulting in more frequent movement of people and goods, further facilitating the spread of the virus.

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When the edges of tectonic plates shift and energy is released, what is the most likely result?

A. Earthquakes
B. Volcanoes
C. Mountain formation
D. Island Formation

Answers

A.Earthquake because of the energy the released

Tectonic Plates are the outer shell of earth, (the lithosphere). Earth's lithosphere is divide into seven plates called tectonic plates.

When the edges of tectonic plates shift and energy is released, then (A) Earthquakes happens.

Result of the tectonic plate shiftingTectonic plates are the layer of the earth's lithosphere.

When tectonic plates shifts and the energy is released, earthquake happens.

Earthquake is the shaking of the earth due to the shifting of the tectonic plates.

Thus, option (A) earthquake is correct.

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10. in humans, the rh factor is inherited as a dominant gene (r). individuals with this allele are referred to as rh positive. two (2) heterozygous individuals (rr) decided to reproduce

Answers

75% of the offspring would be Rh positive (RR or Rr) and 25% would be Rh negative (rr).

When two heterozygous individuals with the dominant rh factor gene (r) reproduce, there is a 75% chance that their offspring will be rh positive (rr or Rr genotype) and a 25% chance that their offspring will be rh negative (rr genotype). This is because each parent has a 50% chance of passing on the dominant r allele, and if both parents pass it on, the offspring will be rh positive. However, if both parents pass on the recessive r allele, the offspring will be rh negative. It is important to note that being rh positive or rh negative has implications for blood transfusions and pregnancy, as an rh negative individual can have an adverse reaction to rh positive blood or the fetus of an rh positive mother if proper precautions are not taken.
Hi! I'd be happy to help with your question. In humans, the Rh factor is inherited as a dominant gene (R). Individuals with this allele are referred to as Rh positive. When two heterozygous individuals (Rr) decide to reproduce, the possible genotypes of their offspring would follow a Punnett square with the following distribution:

- RR (Rh positive): 25%
- Rr (Rh positive): 50%
- rr (Rh negative): 25%

So, 75% of the offspring would be Rh positive (RR or Rr) and 25% would be Rh negative (rr).

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please answer all . I will give a good rate Exercise 6-7 (Algo) Segmented Income Statement [LO6-4] Shannon Company segments its income statement into its North and South Divisions. The company's overall sales, contribution margin ratio, and net operating income are $810,000,32%, and $16,200, respectively.The North Division's contribution margin and contribution margin ratio are $111,600 and 36%,respectively.The South Division's segment margin is $105,000.The company has $170,100 of common fixed expenses that cannot be traced to either division Required: Prepare an income statement for Shannon Company that uses the contribution format and is segmented by divisions.In addition,for the company as a whole and for each segment,show each item on the segmented income statements as a percent of sales.(Round your percentage answers to 1decimal place(i.e .1234 should be entered as 12.3).) Divisions Total Company Amount % North Amount % South Amount %

Answers

The segmented income statement for Shannon Company shows the sales, variable expenses, contribution margin, allocated common fixed expenses, and net operating income for each division. The percentages are calculated by dividing each item by the total sales and multiplying by 100. This segmented statement provides a clear view of the financial performance of each division and the company as a whole.

Segmented income statements provide a detailed breakdown of the financial performance of different divisions or segments within a company. In this case, we have Shannon Company, which consists of two divisions: North and South. The overall sales, contribution margin ratio, and net operating income for the company as a whole are $810,000, 32%, and $16,200, respectively. The North Division has a contribution margin of $111,600 and a contribution margin ratio of 36%, while the South Division's segment margin is $105,000. Additionally, there are $170,100 of common fixed expenses that cannot be traced to either division.

To prepare the segmented income statement, we need to allocate the common fixed expenses to the two divisions. The allocated expenses will be subtracted from the segment margins to arrive at the net operating income for each division. Here is the segmented income statement for Shannon Company:

Shannon Company Segmented Income Statement

Divisions      Total Company        North      South

Amount ($)     % of Sales           % of Sales % of Sales

-------------------------------------------------------

Sales          $810,000             $XXX       $XXX

Variable expenses:

 Variable costs $XXX                 $XXX       $XXX

 Contribution margin $XXX             $XXX       $XXX

Fixed expenses:

 Common fixed expenses allocated:

   North Division   $XXX              $XXX       $XXX

   South Division   $XXX              $XXX       $XXX

Net operating income $16,200            $XXX       $XXX

To calculate the percentages, we divide each amount by the total sales and multiply by 100. The North Division's contribution margin ratio is already given as 36%.

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Which evidence supports the theory of ocean floor spreading?
A) The rocks of the ocean floor and the continents have similar origins.

B) In the ocean floor, rocks near the mid-ocean ridge are cooler than rocks near the continents.

C) The pattern of magnetic orientation of rocks
is similar on both sides of the mid-ocean ridge

D) The density of oceanic crust is greater than the density of continental crust.​

Answers

Answer:

C

Explanation:

Abundant evidence supports the major contentions of the seafloor-spreading theory. First, samples of the deep ocean floor show that basaltic oceanic crust and overlying sediment become progressively younger as the mid-ocean ridge is approached, and the sediment cover is thinner near the ridge.

The evidence supports the theory of ocean floor spreading which is the pattern of magnetic orientation of rocks and is similar on both sides of the mid-ocean ridge.

The theory of ocean floor spreading was formulated in 1960 by Harry Hess after studying different ocean floor patterns and formation.

The oceanic crust forms along submarine mountain zones involves the formation of oceanic crust along mid-ocean ridges which then later spread out to other areas. The farther the oceanic seafloor from the mid-ocean ridges , the older they are.

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if the nucleotide or base sequence of the dna strand used as a template for messenger rna synthesis is acgtt, then what would be the sequence of bases in the corresponding mrna? if the nucleotide or base sequence of the dna strand used as a template for messenger rna synthesis is acgtt, then what would be the sequence of bases in the corresponding mrna? guacc tgcaa acgtt ugcaa

Answers

If the template strand of DNA has the base sequence as ACGTT, then the sequence observed in corresponding m-RNA will be: UGCAA.

DNA stands for Deoxyribonucleic Acid. It is the most abundant form of genetic material present in majority of the living organisms. The structure of DNA is a double stranded helical form where the strands are joined together due to hydrogen bonding between the bases.

m-RNA stands for messenger RNA. It is the form of RNA that contains the genetic information from the DNA, which is required for the synthesis of protein. The strand of m-RNA is complementary to the template DNA strand.

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If the half-life of carbon 14 is about 5730 years, then a fossil that has one-sixteenth the normal production of carbon-14 to carbon-12 should be about how many years old?

Answers

A fossil that has one-sixteenth the normal production of carbon-14 to carbon-12 is most likely very old. This is because carbon-14 has a relatively short half-life of 5730 years, meaning that after this amount of time, half of the amount of carbon-14 in an organism or object would have already decayed.

Since the fossil being discussed has one-sixteenth of the normal production of carbon-14 to carbon-12, this would suggest the fossil is at least 8 times the half-life, or 45,840 years old. Carbon-14 is necessary to measure the age of an object, and due to the fact that this fossil has only one-sixteenth of the normal carbon-14, it can be deduced that it is very old.

It is also possible that the fossil is much older than this calculation, but because of the short half-life of carbon-14, any other amounts which may have been present before the 45,840 year mark has decayed away. In conclusion, a fossil that has one-sixteenth the normal production of carbon-14 to carbon-12 is estimated to be 45,840 years old or older.

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The function of protein is

Answers

Answer:

Protein has many roles in your body. It helps repair and build your body's tissues, allows metabolic reactions to take place and coordinates bodily functions. In addition to providing your body with a structural framework, proteins also maintain proper pH and fluid balance.

-ANime❤

DNA finger printing has dramatically changed the field of ____________________, which is the study of crime scene evidence.

Answers

DNA fingerprinting has dramatically changed the field of forensic science, the study of crime scene evidence.

DNA fingerprinting, also known as DNA profiling or genetic fingerprinting, has revolutionized forensic science by providing a powerful tool for identifying individuals and analyzing crime scene evidence. By comparing DNA samples from crime scenes with potential suspects or DNA databases, forensic scientists can establish links, determine the presence of a specific individual at the scene, and provide valuable evidence in criminal investigations. DNA fingerprinting has greatly enhanced the accuracy and reliability of forensic investigations, helping to solve cold cases, exonerate innocent individuals, and contribute to the administration of justice.

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what recycles matter back into the food web and biogeochemical cycles

Answers

Answer:

A decomposer

Explanation:

WILL GIVE BRAINLIEST. I need help filling this out

WILL GIVE BRAINLIEST. I need help filling this out

Answers

Hope this helps! I added a second cladogram to help with any confusion because I can see how you got stuck with the first one :)
WILL GIVE BRAINLIEST. I need help filling this out

Answer:

i dont know man

Explanation:

lol

FILL THE BLANK. hildegard of bingen was born into a _____ noble of answer choicesgermanfrenchitalianenglish

Answers

Hildegard of Bingen was born into a noble family. She was born into a noble family in the Rhineland region of Germany around the year 1098.

Family refers to a group of individuals who are connected by blood, marriage, or adoption and share a mutual bond, care, and support for one another. Families provide a framework for socialization, emotional support, and the fulfillment of basic needs. They can vary in structure, including nuclear families (parents and children), extended families (including grandparents, aunts, uncles, and cousins), single-parent families, blended families, and more. Family dynamics and relationships can significantly impact individuals' well-being, development, and overall functioning within society.

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think about the advice given in the procedure to test a known catalase positive organism along with an unknownwhat information is provided by the results?

Answers

The procedure to test a known catalase positive organism along with an unknown provides valuable information about the enzymatic activity of the two samples being compared.

The catalase test is a simple, yet essential method used in microbiology labs to identify the presence of the enzyme catalase in a bacterial species. When testing a known catalase positive organism, you can confirm that the procedure is working correctly and validate the test conditions, this positive control ensures that the test environment is accurate and reliable. Meanwhile, the results obtained from testing the unknown organism can provide insights into its potential enzymatic capabilities and classification.

If the unknown organism also tests positive for catalase, this indicates that it can break down hydrogen peroxide into water and oxygen, which is a common trait of aerobic or facultative anaerobic bacteria. A negative result, on the other hand, might suggest that the organism is an anaerobic bacteria or one that lacks the ability to produce the catalase enzyme.  In summary, the results of testing a known catalase positive organism along with an unknown provide information on the presence or absence of the catalase enzyme, allowing for a better understanding of the unknown organism's classification, and ultimately, helping to identify the species more accurately.

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What is an embryo sac?

Answers

A fell inside the ovule of a flowering plant where fertilization occurs and becomes the female gametophyte

identify the characteristics of animals found in the rainforest. (at least 5)

Answers

Answer:

BELOW

Explanation:

For adaptation:

Hiding

Camouflage

Scaring predators

Warning colors

Other information:

One of the reasons for this great variety of animals is the constant warmth. Tropical rainforests also provide a nearly constant supply of water and a wide variety of food for the animals. Small animals, including monkeys, birds, snakes, rodents, frogs, and lizards are common in the tropical rainforest.

e.g. of features:

Animal: short-horned lizard

Sound: hissing sound

Movement: short sprints

Size: small and very small

Coat: scales

Please answer both parts of this question and include a model.
1. Describe this mode of propagation, and draw a model to supplement your description. 2. Explain how it differs from the mode of propagation along the neuron.

Answers

1. In passive propagation, as the action potential goes from the start to the end of an axon, it decays or becomes weaker, and it is the most common method of transmitting electrical signals in neurons. 2. It differs from the mode of propagation along the neuron, the action potential is actively propagated along the axon without decay.

A passive signal can be generated by a receptor or by a spike in the membrane potential of an adjacent neuron. In the neuron, an electrical current flows from the dendrite to the cell body, down the axon and into the terminal, causing a change in the potential across the membrane. The current also generates an electrical field that spreads throughout the surrounding tissue, this electrical field, known as the extracellular potential, decays with distance and is much smaller than the intracellular potential. So therefore a passive signal can be detected by electrodes placed outside the neuron.

An action potential is initiated at the axon hillock, propagated along the axon, and terminates at the presynaptic terminal. In the neuron, an electrical current flows from the dendrite to the cell body, down the axon and into the terminal, causing a change in the potential across the membrane. The current also generates an electrical field that spreads throughout the surrounding tissue, this electrical field, known as the extracellular potential, decays with distance and is much smaller than the intracellular potential. So therefore it differs from the mode of propagation along the neuron, the action potential is actively propagated along the axon without decay.

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transcription of dna to rna can be broken down into three basic steps. what are the three steps in order?

Answers

Codons are complementary groups of bases in mRNA. You can also walk through the steps of transcription in this link. Transcription takes place in three steps: initiation, elongation, and termination.

Plants use different compounds to complete the process of photosynthesis. What do plants give off as a waste product during photosynthesis?

Responses

Carbon dioxide
Carbon dioxide

Nitrogen
Nitrogen

Oxygen
Oxygen

Water

Answers

Answer:

I am a cheater.

Explanation:

I am cheating by looking up the answers to my work on Brainly.

Which process is more important; mitosis or meiosis

Answers

Answer:

Meiosis makes the cells needed for sexual reproduction to occur and Mitosis replicates non-sex cells needed for growth and development. Together, they provide the cellular basis for healthy growth and sexual reproduction.

Explanation:

I majored in Biology

sickle cell anemia is a recessive disorder. if a man who is a carrier for sickle cell anemia has a child with a woman who is normal, what is the probability the child will have sickle cell anemia?

Answers

If a man who is a carrier for sickle cell anemia, the probability the child will have sickle cell anaemia will be zero.

Blood disorders like Sickle Cell Disease are typically hereditary. Because the father can pass on either his normal or his mutated gene to his offspring, and the mother can only pass on her normal gene, if a man who is a carrier for sickle cell anaemia (genotype Ss) has a child with a woman who is normal (genotype ss), their offspring could have either the genotype Ss (carrier) or ss (normal) with equal probability.

Since both parents would need to contribute a defective gene for the kid to have the condition, the likelihood that the infant will have sickle cell anaemia (genotype SS) would thus be zero. Given that there is a 50% chance that the child will receive the mutant gene from the father, the likelihood that the infant will have the sickle cell gene (genotype Ss) is half, or 50%.

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How do clouds affect climate? Check all that are true.A( by producing patterns of precipitation B( by reflecting around one-fourth of the Sun's energy that reaches Earth back into space C( by reflecting most of the Sun's energy back into space D( by producing the same level of precipitation in all climate zones​

Answers

Answer:

i believe its

✓A

✓D

Explanation:

trophoblastic tumor villous decreased syncytiotrophoblast cells, and proliferation of intermediate trophoblast cell -> decrease hcg production

Answers

Villous trophoblastic tumor and decreased syncytiotrophoblast cells, along with the proliferation of intermediate trophoblast cells, are related to a decrease in hCG production.

Human chorionic gonadotropin (hCG) is a hormone that is produced by the placenta after a woman becomes pregnant. It is measured in the blood or urine to confirm pregnancy. A decrease in hCG production can indicate various complications during pregnancy, including a villous trophoblastic tumor and decreased syncytiotrophoblast cells.There are two types of trophoblastic tumors: hydatidiform moles and choriocarcinomas. In villous trophoblastic tumor, the trophoblastic cells within the placenta become abnormal and proliferate excessively. These tumors are typically benign, but they can develop into choriocarcinomas, which are cancerous. The syncytiotrophoblast and intermediate trophoblast cells are two types of trophoblastic cells found in the placenta.

These cells produce hCG, which can be detected in a pregnant woman's blood or urine. In the case of a villous trophoblastic tumor, the trophoblastic cells within the placenta become abnormal and proliferate excessively, causing a decrease in the number of syncytiotrophoblast cells and a subsequent decrease in hCG production.Intermediate trophoblast cells are another type of trophoblastic cell found in the placenta. These cells do not produce hCG. An increase in intermediate trophoblast cells and a decrease in syncytiotrophoblast cells can lead to a decrease in hCG production. This is because the intermediate trophoblast cells are not able to compensate for the loss of syncytiotrophoblast cells and produce enough hCG to maintain pregnancy.

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How does genetic engineering make producing insulin easier compared to when insulin was produced through using a cow pancreas?

Answers

Answer:

It reduces allergic reactions

Explanation:

Insulin could be obtained from animals. This insulin is extracted from animals and then purified for use on humans.

However, genetically engineered insulin is produced by genetically modified bacteria. The advantage of this method of producing insulin is that it yields pure insulin with less allergic reactions in humans.

Can a change in habitat change the variation frequencies of a population?
Yes or no?

Answers

Answer: probly i would say In small populations it unlikely genetic drift will occur but in large populations it’s very likely

Explanation: Depending on population size there is different amounts of genetic variation. That will give different amounts of opportunities to have genes staying alike or becoming different.

yes

competition occurs frequently within habitats. what is the definition of interspecific competition?

Answers

Interspecific competition is a form of competition that occurs between different species living in the same habitat or ecological community.

This competition arises when two or more species utilize the same resources, such as food, water, or living space, in the same ecosystem. The competition can be direct or indirect, and it can occur through interference, exploitation, or both. Direct competition involves physical interactions between individuals, while indirect competition occurs when two species use the same resources but do not interact directly. Interspecific competition can have significant effects on the population dynamics and evolutionary trajectories of the species involved. In some cases, it can lead to the displacement or extinction of one of the competing species, while in other cases, it can lead to the coexistence of the species through niche differentiation or resource partitioning.

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What operation is used when simplifying fractions and conversion units?

Answers

Answer:

  cancellation

Explanation:

A factor in the numerator is cancelled by dividing it by the same factor in the denominator. The quotient is 1, the multiplicative identity element.

QUESTION:

╭☞ What operation is used when simplifying fractions and conversion units?

ANSWER:

╭☞ Cancellation

Explanation: Because factor in the numerator is canceled by dividing it by the same factor in the denominator. The quienty is 1, the multiplicative element of the identity.

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Match the following vocabulary terms to the correct definitions.
multiple monomers
combined together; these
can be referred to as
macromolecules.
found on the periodic table,
one atom of a single type of
matter.
one-SINGLE, subunit of a
polymer
1. Monomer
2. Polymer
3. Element

Match the following vocabulary terms to the correct definitions.multiple monomerscombined together; thesecan

Answers

Answer:

Polymer : multiple monomerscombined together; thesecan be referred to asmacromolecules.Monomer : one-SINGLE, subunit of apolymer.Element : one atom of a single type ofmatter.

What factors would allow a red supergiant star to have the same apparent magnitude as a white dwarf star?

Answers

A star's luminosity and proximity to Earth both affect how bright it seems to be.

Which factor influences the star's apparent magnitude?A star's or another celestial object's apparent magnitude (m), as seen from Earth, is a measurement of brightness. The intrinsic luminosity of an object, its distance from Earth, and any extinction of the object's light by interstellar dust in its line of sight to the observer all play a role in determining its apparent magnitude. Depending on a star's mass, when it departs from the main sequence, the gravitational pressure may be sufficient to trigger the fusion of helium and heavier elements. Supergiants and red giants are created by these stars. The star will become a white dwarf if its mass is insufficient to allow for the fusion of heavier elements.

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Membrane-bound organelles are found in both eukaryotic and
prokaryotic cells.

TRUE

FALSE

Answers

\(▪▪▪▪▪▪▪▪▪▪▪▪▪  {\huge\mathfrak{Answer}}▪▪▪▪▪▪▪▪▪▪▪▪▪▪\)

The Correct choice is ~ False

\( \large \boxed{ \mathfrak{Explanation}}\)

Eukaryotic cells have membrane bound structures but

Prokaryotic cells are primitive cells which don't have membrane bound structures.

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