amino acids with bulky side chains are destabilizing to alpha-helices when they are 4 residues away from each other, but not necessarily when they are directly next to each other. why does this happen? what do you suppose would happen if, instead of bulky amino acids, they were charged. would this be stabilizing or destabilizing to the alpha- helix?

Answers

Answer 1

The destabilizing effect of amino acids with bulky side chains that are 4 residues away from each other is because they cause steric hindrance. As a result, the helix must shift from its ideal conformation, causing a destabilizing effect on the helix.

The impact of charged amino acids on an alpha-helix would be determined by the charge distribution. The electrostatic attraction of oppositely charged residues is the stabilizing force. However, like charges repel each other. When there are multiple like charges in close proximity to each other, there is a destabilizing effect. As a result, if the charged amino acids were spaced out, it would have a stabilizing effect on the helix.

On the other hand, if the charged amino acids are grouped together in close proximity, this would cause a destabilizing effect on the helix. Hence, it can be concluded that if charged amino acids were in place of bulky amino acids, it would depend on their distribution, i.e., if they were spread apart or grouped together.

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Related Questions

"Based on Internet research using the principle of
Uniformitarianism describe possible scenarios of the Supercontinent
Formation in 200 million years. Describe the past Supercontinents
and their evolution

Answers

The following statements are true about persistent organic pollutants like PCBs:

A. They were synthesized and manufactured by humans for purposes such as herbicides, coolant fluids, and hydraulic fluids.

C. They are fat-soluble.

Statement A is true. Persistent organic pollutants (POPs) like PCBs were indeed synthesized and manufactured by humans for various purposes, including their use as herbicides, coolant fluids, and hydraulic fluids. PCBs were widely used in industrial applications due to their chemical stability and electrical insulating properties.

Statement C is also true. POPs, including PCBs, are characterized by their fat solubility. This means that they have a high affinity for fat-containing substances, such as lipids and adipose tissue. Their fat solubility allows them to accumulate in the bodies of organisms, including humans, and persist in the environment for long periods.

However, statement B is not true. POPs like PCBs tend to increase in concentration as they move up the food chain, a process known as biomagnification. This occurs because the organisms at lower trophic levels consume contaminated food sources, accumulating higher concentrations of the pollutants in their tissues. When these organisms are consumed by predators, the pollutants are transferred to the higher trophic levels, leading to an increase in concentration. This biomagnification of PCBs and other POPs is a significant concern due to their potential adverse effects on ecosystems and human health.

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discribe the process of digestion in human body​

Answers

Digestion is the process by which food is broken down into smaller molecules that can be absorbed and utilized by the body.

In the human body, digestion begins in the mouth, where the teeth and enzymes mechanically and chemically break down food in saliva. The partially digested food, called bolus, is then swallowed and travels down the esophagus to the stomach via peristalsis.

In the stomach, the food is mixed with stomach acid and enzymes, further breaking it down. The partially digested food, now called chyme, then moves into the small intestine, where it is mixed with bile (produced in the liver and stored in the gallbladder) and pancreatic enzymes. These enzymes complete the breakdown of the food into small molecules, such as amino acids, glucose, and fatty acids, which can be absorbed by the body.

The remaining indigestible food matter then passes into the large intestine, where water and electrolytes are absorbed before the waste material is eliminated from the body via the rectum and anus.

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Do germinating seeds just starting to germinate consume oxygen/produce carbon dioxide at a greater rate than seeds?

Answers

Yes, the germinating seeds just starting to germinate consume oxygen/produce carbon dioxide at a greater rate than seeds.

Germination is the phenomenon where a seed breaks its dormancy and begins to grow. All the enzymes present inside the seed become active and the outer seed coat starts to rupture. Since the germinating seed needs to grow and develop into a fully grown plant, it need more oxygen and produces more carbon dioxide.

Seeds are the embryonic stage of a plant's life. It consists of stored food reserve, various enzymes that are covered on the outer side by the protective covering called the seed coat.

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the hyperpolarization that occurs at the end of an action potential is due to the prolonged

Answers

The hyperpolarization that occurs at the end of an action potential is due to the prolonged opening of potassium (K⁺) channels and the efflux of potassium ions.

During an action potential, the depolarization phase is primarily driven by the influx of sodium (Na⁺) ions through voltage-gated sodium channels. As the action potential reaches its peak, the voltage-gated sodium channels close, and voltage-gated potassium channels begin to open.

The opening of potassium channels allows potassium ions to move out of the cell, resulting in an efflux of positively charged potassium ions. This efflux of potassium continues even after the membrane potential reaches its resting state.

As a result, the membrane potential becomes more negative than the resting membrane potential, leading to hyperpolarization.


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Substances that are altered by the action of proteases are
known as
1) substrates
2)lipids
3)polysaccharides
4) phosphates

Answers

Answer:

Substances that are altered by the action of proteases are known as: 1) substrates.

Explanation:

Protease is an enzyme, therefore a substrate would have to fit the enzyme, which forms an enzyme-substrate complex. This causes a chemical reaction since enzymes are biological catalysts. Many enzymes often change their shape so that the substrate can fit at the active site.

I hope this makes sense!! ^-^

The suppression of acid secretion is greater with a proton pump inhibitor than with an H2-receptor antagonist because:
A. unlike an H2-receptor antagonist, a proton pump inhibitor blocks the secretion of HCl.
B. unlike an H2-receptor antagonist, a proton pump inhibitor blocks the release of histamine from parietal cells.
C. unlike an H2-receptor antagonist, a proton pump inhibitor increases the volume and strength of acid secretion.
D. unlike an H2-receptor antagonist, a proton pump inhibitor stimulates H1-receptors

Answers

The suppression of acid secretion is greater with a proton pump inhibitor (PPI) compared to an H2-receptor antagonist due to the mechanism of action of PPIs.

Proton pump inhibitor work by irreversibly binding to the hydrogen-potassium ATPase enzyme (proton pump) present in the parietal cells of the stomach. This enzyme is responsible for the final step of acid secretion, which involves pumping hydrogen ions (protons) into the stomach.By inhibiting the proton pump, PPIs effectively block the secretion of hydrochloric acid (HCl) from the parietal cells. This action leads to a significant reduction in gastric acid production.On the other hand, H2-receptor antagonists block the action of histamine on the H2 receptors found in parietal cells. Histamine is one of the signaling molecules that triggers the release of gastric acid.

By inhibiting the H2 receptors, H2-receptor antagonists reduce the amount of acid produced. However, they do not completely halt acid secretion like PPIs do.

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Is it possible today for a eukaryotic cell to live without mitochondria or chloroplasts?

Answers

Answer:

No it is not possible

Explanation:, eukaryotic cells cannot live without mitochondria and chloroplasts; they provide the energy cells need to survive.

The properties of matter depend on the types of atoms a substance is made ofTrue or false

Answers

This statement is true. Properties of a material are a direct consequence of the atoms that constitute it and their interactions.

Which of the following best describes soil texture

Answers

The best definition of the texture of soil would be: Rough and damp
Can you possibly give more details

identify a unique characteristic of a typical cervical vertebra.

Answers

Typical cervical vertebrae have several features distinct from those typical of thoracic or lumbar vertebrae. The most notable distinction is the presence of one foramen, in each transverse process. These transverse foramina encircle the vertebral arteries and veins.

A unique feature of the cervical vertebrae is the presence of one foramen in each transverse process.

What is a cervical vertebra?

Facet joints, which link the seven cervical vertebrae (C1 to C7) at the rear of the bone, allow your neck to move forward, backward, and in a twisted position.

Additionally, there are muscles, nerves, tendons, and ligaments all around your cervical spine. Intervertebral discs, often known as "shock-absorbing" discs, are located between each vertebra. Your whole spine is perforated in the middle by your spinal cord. Your spinal cord transmits and receives information from your brain, which regulates every bodily function.

The vertebral foramen, which extends from the base of your head through your cervical vertebrae, thoracic (middle back) vertebrae, and finishing between the first and the second lumbar (lower back) vertebrae, is the passageway through which the spinal cord's neurons travel. Your spine's stacked vertebrae form a central canal that shields your spinal cord when all of them are together.

Therefore, the presence of one foramen in each transverse process is the distinguishing feature of the cervical vertebrae.

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what kind of hormone stores glucose if its in excesse​

Answers

Answer:

A hormone that tells cells in your liver and muscles to convert glycogen into glucose and release it into your blood so your cells can use it for energy.

To which taxa do all four organisms belong

Answers

All four organisms belong to phylum Chordata, animalia kingdom.

The taxonomic group of creatures known as the Phylum Chordata is distinguished by the development of pharyngeal gill slits, a dorsal nerve cord, and a notochord. Animals classified as chordates differ widely in kind, from fish and amphibians to birds and mammals like humans.

A flexible structure resembling a rod that runs the length of the body, the notochord offers support and facilitates mobility. The animal's back is covered in a ribbon of nerves called the dorsal nerve cord, which carries messages from the brain to the rest of the body.

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What does the presence of gill slits in a human embryo suggest?

Answers

Answer:

The presence of the gill slits suggests that a long time ago humans and fish shared a common ancestor. The similarities between embryos suggest that these animals are related and have common ancestors.

Explanation:

How did Claire’s digestion reaction rates tell you that the problem was in her small intestine, and not her stomach?

How did Claires digestion reaction rates tell you that the problem was in her small intestine, and not

Answers

Absorption of the nutrients will not happen in her small intestine.

Claire’s digestion reaction rates tell you that the problem was in her small intestine, and not her stomach because the intestine is responsible for the absorption of most of the nutrients produced from eating and drinking of food substances.

If the absorption of the nutrients will not happen by the intestine, the whole homeostasis or equilibrium of the body disturbs and no growth of the cell  occurs so we can conclude that absorption of the nutrients will not happen in her small intestine.

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Answer:

Claire’s digestion reaction rates tell you that the problem was in her small intestine, and not her stomach because the intestine is responsible for the absorption of most of the nutrients produced from eating and drinking of food substances.

Explanation:

which statement about the continental drift theory is untrue ?

which statement about the continental drift theory is untrue ?

Answers

Answer:

your right

Explanation:

Answer:

number 4 or D

Explanation:

the plates still shift to this day

Main-group elements from Period 3 of the periodic table are highlighted.
Which element is a highly reactive nonmetal?
11
12
13
14
15
16
17
18
Na Mg
Al Si
P
S
Cl
Ar
Sedium
22.99
04
Magnesium
24.31
Alumis
26.98
Silicon
28 09
Phosphorus
30.97
Argon
Sulu
Chlorine
32.06 35 45 39.95
20134.0131830 18:00 201
13
Al Si P
S Cl Ar
2113
Na Mg
5
3
10
K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr
36
355 67 72837287720.00
44 08.
MATAD
na NA
T
Tu
O A. Argon
B. Aluminum
C. Chlorine
D. Sodium

Main-group elements from Period 3 of the periodic table are highlighted.Which element is a highly reactive

Answers

Answer:

C. Chlorine

Explanation:

A.P.E.X

The element that is highly reactive nonmetal is Chlorine. The correct option is C.

What are non-metals?

Nonmetals are elements that lack metallic properties. They contain colorless gases and some solid.

Chlorine is a non-metal gas, and it is highly reactive because it is a halogen.

Thus, the correct option is C, chlorine.

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Brown lizard that has invaded some areas of Florida​

Answers

please write a clear and appropriate question

Answer:

Brown Anole

Explanation:

Hope it helps.

What is a Fungi’s response to outside is known as what

Answers

Answer:

Tendency of fungi to grow toward or away from a source of light. gravitropism. A fungi's response to gravity in which stems grow upward and roots grow downward.

Answer: phototropism.

Explanation: Fungi  grows toward or away from a source of light. gravitropism. A fungi's response to gravity in which stems grow upward and roots grow downward.

answer all 3 please

answer all 3 please

Answers

Answer: 1. Earthquake

2. Lava

3. Divergent Boundary

Explanation:

the wet bulb temperature is 10 C the Dry bulb temperature is 14 C what is the relative humidity?

Answers

The relative humidity is approximately 22.9% based on the given wet bulb temperature of 10°C and dry bulb temperature of 14°C.

Relative humidity

Wet bulb temperature: 10°C = 50°F

Dry bulb temperature: 14°C = 57.2°F

SVP at wet bulb temperature: 0.284 * \(e^(17.27 * 10 / (10 + 237.3))\)= 0.284 * \(e^(-7.09)\) = 0.284 * 0.000828 = 0.0002356 psi

SVP at dry bulb temperature: 0.284 *\(e^(17.27 * 14 / (14 + 237.3))\) = 0.284 * e^(-5.97) = 0.284 * 0.002562 = 0.0007296 psi

AVP = 0.0002356 - (0.00066 * (57.2 - 50) * 14.7) = 0.0002356 - (0.00066 * 7.2 * 14.7) = 0.0002356 - 0.0686 = 0.000167 psi

RH = (AVP / SVP at dry bulb temperature) * 100

RH = (0.000167 / 0.0007296) * 100 = 0.229 * 100 = 22.9%

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Each peak in the waveform corresponds to a different _______.

Answers

Each peak in the waveform corresponds to a different Length fragment into reaction.

What does a waveform mean?

Alternating current (AC) waveforms show how AC changes over time. The sine wave, which gets its name from how the current or voltage varies with the sine of the passing time, is the most well-known type of AC waveform.

What waveform is the output?

A sinusoidal input at the terminal for non-inverting input. the input terminal for the inverting device's ground voltage. As far as we are aware, the sinusoidal signal is positive for one half cycle and negative for the next. The output will fluctuate between + Vcc and -Vcc. Consequently, a square wave will be the result.

What are the three types of waveforms?

Independent output terminals simultaneously provide access to the sinusoidal, triangular, and square waveform outputs.

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which two structures clearly divide the forearm flexors from the extensors?

Answers

The two structures that clearly divide the forearm flexors from the extensors are: Medial Epicondyle, Lateral Epicondyle.

The medial epicondyle is a bony prominence on the inner side of the humerus bone, located at the elbow joint. It serves as the attachment site for several flexor muscles of the forearm, including the pronator teres and flexor carpi radialis.

The lateral epicondyle is another bony prominence on the outer side of the humerus bone, also situated at the elbow joint. It provides attachment points for the extensor muscles of the forearm, such as the extensor carpi radialis brevis and extensor digitorum.

These structures serve as anatomical landmarks that clearly separate the muscles responsible for forearm flexion from those involved in forearm extension.

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identify an independent variable in the experiment graphed in figure 1. based on the data in figure 1, identify a control that shows that sepin-1 rather than something else in the culture medium is inhibiting that growth of the cancer cells

Answers

Answer:

Explanation:

This question is incomplete because of the absence of the graph. However, the independent variable of an experiment is the variable that is not affected by any other variable during the course of the experiment but is however intentionally or unintentionally predetermined by the researcher conducting the experiment. For example, in an experiment to determine the effect of age on blood pressure; age is the independent variable because the age class/groups of the individuals to be used can be determined by the researcher also the age cannot be affected by the pressure (the age of a person cannot change because of an increase/decrease in blood pressure).

Also, the control of an experiment is the variable/data in which other data in the same experiment are compared to. For example, in an experiment to determine the effect of a substance (such as sepin-1) on the growth of cancer cells (using a culture medium), the control can be the culture medium that was not given any substance or the culture medium that was given a pure substance of no effect like water. This means, in this control culture medium, the cancer cells will continue to grow normally while that growth will be compared with what is seen in the culture medium treated with sepin-1.

I need help because this is important for my grade

I need help because this is important for my grade

Answers

Seasons are determined by the Earth's revolution around the sun and its obliquity.

What are seasons determined by?

Seasons are determined two significant factors revolution, which is the way in which the earth orbits around the sun. obliquity, which is the inclination of the Earth's axis.

Obliquity refers to the plane in which the Earth moves around the sun, which has an inclination angle called ecliptic obliquity. It is not orthogonal to the rotation axis.

Depending on the location of the Earth concerning the sun, it receives more radiation in the nothern or southern hemisphere.

Also, we have the following seasons

Fall ⇒ shorter day time, lower radiation, colder.Winter ⇒ shortest day time, lowest radiation, lowest temperatureSpring ⇒ longer day time, more radiation, warmerSummer ⇒ longest day time, the highest radiation, highest temeperature

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Which of these are examples of negative tropism? (Select all that apply.) Plant roots growing toward a water source due to hydrotropism. Plant leaves and stems growing away from light due to phototropism. Plant leaves and stems growing toward light due to phototropism. Plant roots growing down into the dirt due to gravitropism. Plant roots growing toward the surface of the soil due to gravitropism. Plant roots growing away from a water source due to hydrotropism

Answers

Answer:

Plant leaves and stems growing away from light due to phototropism.

Plant roots growing away from a water source due to hydrotropism

Explanation:

When we are talking about tropism, it is refer to as the response or directional growth or response of plants to stimulus.

We have positive and negative tropism.

The negative tropism occur when plants grow away from the stimulus while positive tropism is when plants grows towards the response of stimulus.

Therefore from the question, negative tropism are

Plant roots growing away from a water source due to hydrotropism

Plant leaves and stems growing away from light due to phototropism.

Answer:

Plant leaves and stems growing away from light due to phototropism.

Plant roots growing away from a water source due to hydrotropism

Explanation:

ARTS :


true. or. false. ​

ARTS :true. or. false.

Answers

Answer:

true false true false true

what time of year are date palms usually pollinated?

Answers

Date palms are generally pollinated during the spring season. This is the time when the male flowers produce pollen and the female flowers receive it.

Date palm pollination is wind pollinated but is not very effective so it is usually done artificially. Hand pollination is done by collecting pollen from the male flowers and then applying it to the female flowers through a process called dusting. This is typically done in the months of March and April, during the spring season and in the fall almost a year after flowering, they mature.

The date is an elongated fruit, measuring 2.5 to 8 cm, yellow at first and later reddish brown, with a single very hard stone with a deep longitudinal groove.

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Describ how matter moves throghout the owl’s food web.

Answers

Plants absorb the nutrients through their roots. When main consumers eat the plants, the nutrients are transferred to them. When higher level consumers eat lower level consumers, the nutrients are transferred. The cycle is repeated after death.

What is a Food web ?

All the food chains in one ecosystem are combined to form a food web. Every living organism in an ecosystem is connected to several different food chains. Each food chain represents a potential route that energy and nutrients could follow as they circulate throughout the ecosystem.

The sum of all the food chains in an ecosystem is known as a food web. A mouse eating a plant and then getting eaten by an owl might be an example of a regular food chain. But the mouse isn't the only one consuming the vegetation. Probably a wide variety of creatures are devouring them.

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In the carbon cycle, several processes contribute to the movement of carbon through the ecosystem. For each of the types of movement below, name the process in the carbon cycle that accomplishes it: A. Movement of carbon from the atmosphere into living organisms: ___________________ B. Movement of carbon from living organisms into the atmosphere: ___________________ C. Movement of carbon between different organisms due to feeding: ____________________

Answers

Answer:

A. Movement of carbon from the atmosphere into living organisms: PHOTOSYNTHESIS

B. Movement of carbon from living organisms into the atmosphere: RESPIRATION.

C. Movement of carbon between different organisms due to feeding: DECOMPOSITION

Explanation:

Carbon is the main element in the compounds that make up living organisms. It is found in the remains of living organisms, fossil fuels, inorganic salts, water bodies and air. It is continuously being removed from and added to the carbondioxide in the atmosphere.

The CARBON CYCLE is defined as the process which brings about the circulation of carbon compounds in nature. These processes include:

--> PHOTOSYNTHESIS: Green plants (producers) are continuously removing carbon dioxide from the atmosphere for photosynthesis. The carbon of the carbon dioxide is incorporated into sugars and other complex organic compounds in plants' tissues. When the plants are eaten by animals (primary consumers), the plant material is digested, absorbed and built up into compounds which form animal tissues. Thus, this accomplishes movement of carbon between different organisms due to feeding.

--> RESPIRATION: Plants and animals respire all the time to obtain energy. During this process, sugar are broken down to liberate carbondioxide and water as wastes. Thus this accomplishes the movement of carbon from living organisms back into the atmosphere.

--> DECOMPOSITION: This is a process in carbon cycle where decomposers feed on the dead and decaying organisms and their excreta and bring about their decomposition. They have enzymes that break down organic compounds into simple inorganic compounds. Although inorganic compounds (carbondioxide) are released during decay, decomposers absorb these compounds for their own use. When decomposers doe, othe decomposers feed on them thereby accomplishing the movement of carbon between different organisms due to feeding.

is table salt a compound? how can you tell?​

Answers

Answer: Salt is an ionic compound, consisting of a crystal, lattice structure of the two ions Na+ and Cl-. Salt water is full of sodium chloride molecules.

Explanation:

hope this helps

Answer:

Chemically, table salt consists of two elements, sodium (Na) and chloride (Cl). Neither element occurs separately and free in nature, but are found bound together as the compound sodium chloride.

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