Answer:
critical obstacle to developing effective medications to prevent and/or treat alcohol use disorders is the lack of specific knowledge regarding the plethora of molecular targets and mechanisms underlying alcohol (ethanol) action in the brain. To identify the role of individual receptor subunits in ethanol-induced behaviors, we developed a novel class of ultra-sensitive ethanol receptors (USERs) that allow activation of a single receptor subunit population sensitized to extremely low ethanol concentrations. USERs were created by mutating as few as four residues in the extracellular loop 2 region of glycine receptors (GlyRs) or γ-aminobutyric acid type A receptors (GABAARs), which are implicated in causing many behavioral effects linked to ethanol abuse. USERs, expressed in Xenopus oocytes and tested using two-electrode voltage clamp, demonstrated an increase in ethanol sensitivity of 100-fold over wild-type receptors by significantly decreasing the threshold and increasing the magnitude of ethanol response, without altering general receptor properties including sensitivity to the neurosteroid, allopregnanolone. These profound changes in ethanol sensitivity were observed across multiple subunits of GlyRs and GABAARs. Collectively, our studies set the stage for using USER technology in genetically engineered animals as a unique tool to increase understanding of the neurobiological basis of the behavioral effects of ethanol.
Explanation:
make me as brain liest
in the years leading up to the civil war, how did the article you read describe the situation with the institution of slavery in texas? group of answer choices many white texans believed slavery was key to the texas economy all of these statements are true it was confined mostly to eastern texas and the counties north of houston and galveston people owning slaves was rare outside of eastern texas
On March 2, 1861, Texas formally joined the fledgling Confederacy as the seventh state. Gov. Sam Houston opposed secession and struggled with his allegiances to his new state as well as his country.
His refusal to swear an oath of allegiance to the new administration was due to his strong belief in the Union, which lost him his position. Texas was required to re-join the United States of America after the Confederate States were defeated in the American Civil War. Beginning on June 19, 1865, soldiers from the Union Army assumed formal control of the region. Texas was not an exception to the early American tradition of enslaving African Americans. Even though the Mexican government condemned slavery, Texas had 5000 slaves by the year 1850. the year 1836, during the Texas Revolution. Slavery existed in the earliest societies (such as Sumer in Mesopotamia, which dates back as far as 3500 BC). The Mesopotamian Code of Hammurabi (circa 1750 BC) mentions slavery and describes it as an established institution.
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What was one outcome of the debate between the Federalists and Anti-Federalists over the ratification of the Constitution?
The Anti-Federalists opposed the formation of a strong national government and opposed ratification, while the Federalists advocated for a strong union and the acceptance of the Constitution.
What exactly is a Federalist?The Federalist Party was an early national political party in the United States that campaigned for a strong central government and held power from 1789 until 1801, during the country's political party system's beginnings.
The term federalist was initially used in 1787 to identify proponents of the newly written Constitution who stressed the intended union's federal character. Between October 1787 and August 1788, Alexander Hamilton, John Jay, and James Madison published a series of 85 pieces under the pseudonym "Publius" in various New York newspapers.
The Federalist papers (officially The Federalist), as the collection of essays, is known, were produced to challenge Anti-Federalism and persuade the people of the Constitution's importance.
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Which factor would credit card companies most likely use to determine applicants credit worthiness
The factor that credit card companies would most likely use to determine an applicant's creditworthiness is their hourly wages.
What is most important factor in determining an applicant's creditworthiness?These companies assess an individual's creditworthiness by looking at their credit history and score because they provides insight into the individual's past credit behavior such as their payment history, amount of debt, length of credit history, and types of credit used etc.
A high credit score indicate to credit card companies that he individual is a responsible borrower and is more likely to repay their debts on time but low credit score indicate to credit card companies that an individual is a risky borrower.
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There is a baseball in my drive way . My car windshields is broken. Someone playing ball. Someone playing ball must be shattered my windshield. Which one is a inference?
Answer:
Someone playing ball must have shattered my windshield
Explanation:
To make an inference you have to reach a conclusion using evidence and reasoning.
help please will give brainlyest
Which country had the largest colonial empire at one time?
France
Great Britain
Germany
United States
Answer:
B. Great Britain
Explanation:
Hope it is useful
Which of the following best explains the reason for the deployment of United States troops overseas at the time when this act was passed?
A
The concern over German aggression in Europe
B
The desire to gain political control over new colonial territories
C
The attempts to overthrow Soviet domination in Eastern Europe
D
The fear of the expansion of communism to foreign nations
The reason for the deployment of United States troops overseas at the time when this act was passed was the fear of the expansion of communism to foreign nations. The answer is D.
The act referred to in this question is likely the Mutual Defense Assistance Act of 1949, which authorized military aid to U.S. allies in order to contain the spread of communism.
This act was passed during the early years of the Cold War, a period of heightened tension between the United States and the Soviet Union. The United States saw the spread of communism as a threat to its national security and sought to prevent its expansion through a policy of containment.
In order to implement this policy, the United States deployed troops overseas to countries such as Greece and Turkey, which were seen as vulnerable to Soviet influence. The United States also provided military aid to other countries, including South Korea and Vietnam, in order to support their efforts to resist communist aggression.
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legislation that was passed in 1964 as a result of the march on washington
The Civil Rights Act was passed in 1964 as a result of the march on Washington.
The Civil Rights Act of 1964 was passed in June 1964 as a result of activist agitation for years in support of comprehensive civil rights legislation. Prior to the March on Washington, President Kennedy had presented the civil rights measure to Congress, but it was held up in the Judiciary Committee by Southern senators' stalling tactics. The Civil Rights Act of 1964 forbade segregation and discrimination in employment, public accommodations, housing, and education.
It created a federal Community Relations Service to help local communities with civil rights issues and the Equal Employment Opportunity Commission to promote equitable hiring practises. The bill also gave the US Office of Education permission to provide financial support to areas that are battling to desegregate their public schools.
The question seems incomplete. The complete question is:
Which legislation was passed in 1964 as a result of the March on Washington?
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Research and explain the steps to legally immigrate to America today.
No links
Need this ASAP
which one is the most important document? (i’ll give 10 points)
- The Declaration of Independence
- The Bill of Rights
- The Magna Carta
- The Declaration of the Rights of Man
The Magna Carta is one of the most important document.
In the lengthy historical process that resulted in the rule of constitutional law as it exists now in the English-speaking world, the Magna Carta was undoubtedly the most important early influence. King John of England was forced to sign the Magna Carta, which outlines what are now known as human rights, by his subjects in 1215 after he broke a number of old rules and practises that had previously been used to govern England.
It contains clauses outlawing governmental misconduct and bribery. The Magna Carta, which is regarded by many as one of the most significant legal document in the growth of modern democracy, marked a pivotal turning point in the fight for freedom.
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Which of these choices is the general study of where people, places, and things are located and how they relate to each other?
Answer:
Firstly I thought about cartography, because maps show us various places and points of interest, but it doesn't show the relation of such points. That's why I think the study you're asking for is geography which focuses on all mentioned factors and tries to find an answer of what connects them.
which step did peter the great take because of his fear of the church?
Peter brought the church under his control, repositioned the capital, and enacted numerous changes to make Russia more akin to European states.
How did Peter the Great weaken the church's influence?
The patriarch served as the church's senior priest. The way the church was run was significantly altered when Peter the Great assumed leadership. He erected a number of new churches. In addition, he deposed the patriarch and placed the church under state authority.
What cause did Peter the Great defend?
As he came to be known, Peter the Great led his nation into protracted wars with Persia, the Ottoman Empire, and Sweden. Peter's realm was significantly expanded by Russian wins in these conflicts, and Sweden's fall provided direct access for Russia.
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What was the name of the first major sub-Saharan civilization?
The name of the first major sub-Saharan civilization on Africa Continent is the "Kingdom of Kush".
What is the Kingdom of Kush civilization?This Kingdom was an ancient kingdom in Nubia which was centered along the Nile Valley in what is now northern Sudan and southern Egypt. The region was an early cradle of civilization that produced a several complex societies that engaged in trade and industry.
The city emerged as the dominant political force between 2450 and 1450 BC by controlling the Nile Valley between the first and fourth cataracts an area as large as Egypt.
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Can someone please give me the purpose and bias of the “We’re fighting to prevent this” poster?
The purpose of the "We're fighting to prevent this" poster is to raise awareness and mobilize support, while bias is indeterminable without further information.
To accurately analyze the purpose and bias of a specific poster, it is necessary to have the visual representation or detailed description of the "We're fighting to prevent this" poster. Without the actual content of the poster, it is challenging to provide a comprehensive analysis. Posters are visual communication tools that convey messages, opinions, or aims through imagery, text, and design elements. The purpose of a poster can vary widely, from raising awareness about a specific issue to promoting a particular ideology or viewpoint. The bias of a poster refers to any intentional or unintentional slant or distortion in the presentation of information, often driven by the creator's perspective, beliefs, or agenda. The purpose of the "We're fighting to prevent this" poster is to advocate for a cause or issue and motivate viewers to take action. The poster aims to raise awareness about a particular problem or threat and to rally support for efforts to prevent it. It likely intends to evoke a sense of urgency and concern among the audience, urging them to join the fight against the depicted issue.Regarding bias, it is important to note that without specific information about the content or context of the poster, it is challenging to determine its exact bias. However, as with any communication medium, there is a possibility of bias. The poster might present a biased perspective by focusing on one side of the issue, omitting certain information, or using emotionally charged language or imagery to sway opinions. It is crucial for the audience to critically evaluate the message and consider alternative viewpoints to have a well-rounded understanding of the issue at hand.For more questions on poster
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Please select the word from the list that best fits the definition
means “protector of the kingdom”
Answer:
satrap
Explanation:
TRUE / FALSE. the ""peaceful revolution"" refers to the inauguration of thomas jefferson.
FALSE. The "peaceful revolution" refers to the transfer of power from the Federalist Party to the Democratic-Republican Party in the 1800 presidential election, which resulted in the inauguration of Thomas Jefferson.
The term "peaceful revolution" is often used to describe the transfer of power from the Federalist Party to the Democratic-Republican Party in the United States in 1800. This was a significant event in American history, as it marked the first time that power had been transferred between political parties without violence or bloodshed. In the election of 1800, Thomas Jefferson, a Democratic-Republican, defeated incumbent Federalist President John Adams. The peaceful transfer of power from one party to another was a significant moment in the development of American democracy, as it demonstrated that political differences could be resolved peacefully and through the democratic process. This event paved the way for future peaceful transfers of power in American politics.
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Why did George Washington have his men cross the Delaware River on
Christmas night in 1776
Answer:
Washington crossed the Delaware River so that his army could attack an isolated garrison of Hessian troops located at Trenton, New Jersey. ... After several councils of war, General George Washington set the date for the river crossing for Christmas night 1776.
Explanation:
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Answer:
so that his army could attack an isolated garrison of Hessian troops located at Trenton, New Jersey. ... After several councils of war,
Select the correct answer.
Which European nation colonized India and Australia, in addition to having spheres of influence in China?
A.
Germany
B.
Spain
C.
Great Britain
D.
France
Answer: the correct answer is (C) Great Britain
Explanation:
Which economic approach did the united states adopt toward foreign trade during the 1920s?
a. isolated to domestic markets
b. expansion into global markets
c. transition from agricultural to manufacturing jobs
d. installment buying
Answer:
B.expansion into global markets
How many milliliters of a 0.250 M solution can be prepared by dissolving 4.00 g of NaCl in water?
The 274 milliliters of a 0.250 M solution can be prepared by dissolving 4.00 g of NaCl in water.
To calculate the number of milliliters of a 0.250 M solution that can be prepared by dissolving 4.00 g of NaCl in water, we need to use the formula:
Molarity = moles of solute / volume of solution (in liters)
First, we need to calculate the moles of NaCl present in 4.00 g. The molar mass of NaCl is 58.44 g/mol. Therefore,
moles of NaCl = 4.00 g / 58.44 g/mol = 0.0684 mol
Now, we can use the formula to find the volume of the solution:
0.250 M = 0.0684 mol / V (in liters)
V (in liters) = 0.0684 mol / 0.250 M = 0.274 L
Finally, we convert the volume from liters to milliliters:
0.274 L x 1000 mL/L = 274 mL
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How did the great depression (American economic crisis) affect (the weimer republic) and how it made hitler win the elections: germany
The Great Depression's economic hardships and political disillusionment in the Weimar Republic provided fertile ground for Hitler's rise to power in Germany.
The Great Depression had a significant impact on the Weimar Republic in Germany and contributed to Hitler's rise to power. The economic crisis led to high unemployment rates, widespread poverty, and political instability in Germany. Dissatisfaction with the government's handling of the crisis and perceived failures of the democratic system created fertile ground for extremist ideologies to gain support.Hitler capitalized on the discontent by offering simple solutions, scapegoating minorities, and promising economic recovery and national pride. His populist rhetoric resonated with many Germans who were disillusioned with the existing political establishment. The economic hardships of the Great Depression provided a breeding ground for Hitler's Nazi Party, allowing it to gain popularity and ultimately win elections as Germans sought a radical change in leadership and economic stability.The Great Depression's impact on the Weimar Republic was devastating, as it exacerbated economic hardships, social unrest, and political disillusionment. In this vulnerable climate, Adolf Hitler skillfully exploited the economic crisis to rally support for his extremist ideologies, ultimately leading to his electoral success and the erosion of democracy in Germany.For more questions on the Great Depression, visit:
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how many ice ages do scientist estimate have occurred during the last billion years
Scientists estimate that there have been approximately five major ice ages in the last billion years.
These ice ages are characterized by long periods of reduced temperatures and extensive glaciation on Earth. The five major ice ages include the Huronian, Cryogenian, Andean-Saharan, Karoo, and the current Quaternary ice age.
The Quaternary ice age began around 2.58 million years ago and continues to the present day. During ice ages, Earth experiences glacials and interglacials. Glacials are colder periods with increased ice coverage, while interglacials are warmer periods with less ice coverage. Currently, we are in an interglacial period called the Holocene epoch.
Understanding ice ages and their impacts on Earth's climate, geology, and ecosystems is crucial for scientists to comprehend the long-term climate variations and predict future climate changes. The study of ice ages also provides insights into the ways Earth's climate and biosphere have adapted and evolved over time.
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Scientists estimate that there have been approximately five major ice ages in the last billion years.
These ice ages are characterized by long periods of reduced temperatures and extensive glaciation on Earth. The five major ice ages include the Huronian, Cryogenian, Andean-Saharan, Karoo, and the current Quaternary ice age.The Quaternary ice age began around 2.58 million years ago and continues to the present day. During ice ages, Earth experiences glacials and interglacials. Glacials are colder periods with increased ice coverage, while interglacials are warmer periods with less ice coverage. Currently, we are in an interglacial period called the Holocene epoch.Understanding ice ages and their impacts on Earth's climate, geology, and ecosystems is crucial for scientists to comprehend the long-term climate variations and predict future climate changes. The study of ice ages also provides insights into the ways Earth's climate and biosphere have adapted and evolved over time.
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Clarissa reads the passage on invasive species above and then writes four different answers to the question that follows. Which answers complies with ut high school's policy on scholastic honesty?
Complying with UT High School's policy on scholastic honesty, it is important to provide original and independent answers to the question based on one's own understanding and analysis. Therefore, I will provide four different answers to the question without resorting to plagiarism or copying from external sources.
1. Answer 1 (Original): Invasive species pose a significant threat to ecosystems by outcompeting native species for resources and disrupting the natural balance. They often lack natural predators or controls, allowing them to reproduce rapidly and dominate their new environments. This can lead to the decline or extinction of native species, disrupt ecological processes, and harm the overall health and biodiversity of ecosystems.
2. Answer 2 (Original): Invasive species are non-native organisms that have been introduced to an ecosystem, either intentionally or unintentionally, and have a negative impact on the native species and habitats. They can cause ecological and economic damage by outcompeting native species, altering habitats, spreading diseases, and reducing biodiversity. Effective management and control strategies are crucial to mitigate the harmful effects of invasive species.
3. Answer 3 (Original): The introduction of invasive species can have severe consequences for ecosystems. They can disrupt food chains, alter habitats, and reduce biodiversity. Invasive species often possess traits that give them a competitive advantage over native species, allowing them to spread rapidly and dominate their new environments.
4. Answer 4 (Original): Invasive species are a significant ecological concern as they can cause substantial harm to native ecosystems. Their introduction can result in the displacement or extinction of native species, leading to imbalances in the natural communities. Invasive species can also impact human activities, such as agriculture, forestry, and recreation.
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QUESTION 3:
Why were Spanish weaknesses so significant in the defeat of the Spanish Armada?
[12 marks]
Answer:
The Armada was difficult to attack because it sailed in a 'crescent' shape. while the armada tried to get touch with the Spanish army, the English ship attacked fiercely. however, an important reason why English were able to defent the armada was that the wind blew the Spanish ships northwards.
[Public Ocriunces} !READ ALL ABOUT it! Are you tired of the mistreated people in in this cold cruel word it's is hard for them as its hard for you , Such as if you see a Mother mistreating their child infront of you you might want to tell the mother "he or she is just a kid what do you want out of them?" or"Screaming isn't gonna help. My point here you want to protect that child same as you want to protect that person. Its unfair this world. Its hope we need to find to help them. - piper write
The passage encourages readers to be compassionate towards mistreated people and emphasizes the need to take action to protect and support them.
The paragraph expresses worry over how people are treated across the world and calls on readers to take action. It offers an illustration of seeing a mother abusing her child and proposes retaliating with kindness and safety. The author understands the challenges that abused individuals and readers both encounter.
The author stresses the importance of having hope and figuring out how to assist individuals who are mistreated. In general, the paragraph exhorts readers to recognise wrongdoing and take action to safeguard and help others.
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What are economic impacts caused by the Persian war
The economic impacts caused by the Persian war a large possible of the Persian fleet was destructed. They also the impact of the military supplies and civilian losses.
What is economic?The term economic refers to the process of production, distribution, and consumption activities. The main components of economies are products and services. The primary sector of the economy is the industrial sector.
The economic impacts caused by the Persian war was the countries exceeded 500 billion U.S. dollars and mainly the losses on civilian and the military supplies.
As a result, the significant of the economic are the aforementioned.
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describe one change in voter registration that occured between march 1965 and september 1967 frq quizler
Why did the United States rebuild West Germany after
World War Il?
Not just Germany, but other European countries received large loans from the United States, which enabled them to pay for the large inflows of imports which were crucial for postwar recovery.
Our country needs so that individual rights so that
Answer:
our country should have a certain amount so people don't mess with them and it helps our country so much.
Explanation:
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civil war within liberia in the first decade of the twentieth century also led to many deaths in:
The civil war within Liberia in the first decade of the twentieth century also led to many deaths in neighboring Sierra Leone.
The war in Sierra Leone, which lasted from 1991 to 2002, resulted in the displacement of many Sierra Leoneans, who sought refuge in neighboring countries, including Liberia. The conflict was characterized by brutal violence, including the use of child soldiers and amputations. Liberian mercenaries and rebel groups were also involved in the conflict, exacerbating tensions between the two countries. The war in Sierra Leone eventually ended with the intervention of international peacekeeping forces, but the legacies of the conflict continue to affect both Sierra Leone and Liberia.
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The civil war within Liberia in the first decade of the twentieth century also led to many deaths in neighboring countries such as Sierra Leone and Guinea, as well as displacement of thousands of people. The conflict was primarily fought between the Americo-Liberian ruling elite and indigenous ethnic groups, with tensions stemming from the unequal distribution of power and resources. The war lasted from 1909 to 1911 and resulted in the death of thousands of people, both combatants and civilians. It also contributed to the destabilization of the region and the emergence of armed groups and warlords.